| Identification |
|---|
| BMDB Protein ID
| BMDBP00650 |
| Secondary Accession Numbers
| None |
| Name
| Cytosolic non-specific dipeptidase |
| Synonyms
|
Not Available
|
| Gene Name
| CNDP2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Amino acid transport and metabolism |
| Specific Function
| Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis. |
| Pathways
|
- beta-Alanine Metabolism
- Histidine Metabolism
|
| Reactions
|
| Anserine + Water → Beta-Alanine + 3-Methylhistidine |
details
|
| Carnosine + Water → Beta-Alanine + L-Histidine |
details
|
| Anserine + Water → Beta-Alanine + 1-Methylhistidine |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 24 |
| Locus
| Not Available |
| SNPs
| CNDP2 |
| Gene Sequence
|
>1428 bp
ATGTCGGCCCTCACCACCCTGTTTAAGTACGTGGACGAAAATCAGGATCGATATGTTAAG
AAGCTTGCGGAATGGGTGGCCATCCAGAGCGTGTCAGCGTGGCCAGAGAAGAGAGGCGAG
ATCCGCAGGATGATGGAGGTGGCGGCCGCCGACATCAAGCAGCTGGGCGGCTCTGTGCAG
CTGGTGGACATCGGGACCCAGAAGCTCCCTGATGGCTCCGAGATCCCACTTCCGCCCATT
TTACTCGGCAAGCTGGGCTCTGACCCACAGAAGAAGACGGTGTGCATCTACGGCCACCTG
GACGTGCAGCCGGCGGCCCTGGAGGACGGCTGGGACAGCGAGCCCTTCACCCTGGTGGAG
CGAGACGGCAAACTGTTTGGGAGAGGAGCCACCGACGACAAGGGGCCGGTGGCCGGCTGG
ATCAATGCCCTGGAAGCCTTCCAGAAAACCAAGCAGGAAGTCCCGGTCAACGTCCGCTTC
TGCCTGGAGGGCATGGAGGAGTCGGGCTCCGAGGGCCTGGACGCGCTGATCTTCGCGCAG
AAAGACGCATTCTTCAAGGATGTGGACTACGTGTGCATCTCCGACAACTACTGGCTGGGC
AAGAACAAGCCCTGCATCACCTACGGGCTGCGGGGCATCTGCTACTTCTTCATCGAGGTG
GAATGCAGCGACAAGGACCTGCACTCGGGCGTGTACGGCGGCTCGGTGCACGAGGCCATG
ACCGACCTCATCATGCTGATGGGCTGCCTGATGGACAAGAAGGGGAAGATCCTCATCCCG
GGCATCAGTGAGGCCGTGGCCCCCGTGACCGAGGAGGAGCTGGAGCTCTACGACAAGATC
GATTTTGACCTGGAGGAGTACGCCCGGGACGTGGGCGCTGGGACCCTCCTGCATGGCTGC
AAGAAGGACATCCTGATGCACAGATGGCGTTACCCATCCCTGTCTCTTCATGGCATCGAA
GGTGCCTTCTCCGGGTCAGGGGCCAAGACCGTGATTCCACGAAAGGTGGTCGGCAAGTTC
TCCATCCGACTCGTCCCGAACATGACTCCGGAAGTGGTCAGCGAGCAGGTTACAAGCTAC
TTGACCAAGAAGTTTGCTGAGCTTCACAGTCCCAACAAGTTCAAGGTGTACATGGGCCAC
GGCGGGAAGCCCTGGGTGTCCGACTTCAACCACCCTCACTACCTGGCTGGGAGGAGGGCC
CTGAAGACAGTGTTTGGTGTCGAGCCGGACTTGACCAGGGAAGGCGGCAGCATCCCAGTG
ACACTGACGTTCCAGGAGGCCACAGGCAAGAACGTCATGCTGCTGCCCGTGGGCTCGGCG
GACGACGGAGCGCACTCCCAGAACGAGAAGCTCAACCGGCGCAACTACATTGAGGGGACC
AAGATGCTGGCCGCGTACCTGTACGAAGTCTCCCAGCTGAAGGACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 475 |
| Molecular Weight
| 52655.0 |
| Theoretical pI
| 5.67 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Cytosolic non-specific dipeptidase
MSALTTLFKYVDENQDRYVKKLAEWVAIQSVSAWPEKRGEIRRMMEVAAADIKQLGGSVQ
LVDIGTQKLPDGSEIPLPPILLGKLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTLVE
RDGKLFGRGATDDKGPVAGWINALEAFQKTKQEVPVNVRFCLEGMEESGSEGLDALIFAQ
KDAFFKDVDYVCISDNYWLGKNKPCITYGLRGICYFFIEVECSDKDLHSGVYGGSVHEAM
TDLIMLMGCLMDKKGKILIPGISEAVAPVTEEELELYDKIDFDLEEYARDVGAGTLLHGC
KKDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPNMTPEVVSEQVTSY
LTKKFAELHSPNKFKVYMGHGGKPWVSDFNHPHYLAGRRALKTVFGVEPDLTREGGSIPV
TLTFQEATGKNVMLLPVGSADDGAHSQNEKLNRRNYIEGTKMLAAYLYEVSQLKD
|
| External Links |
|---|
| GenBank ID Protein
| AAI02836.1 |
| UniProtKB/Swiss-Prot ID
| Q3ZC84 |
| UniProtKB/Swiss-Prot Entry Name
| CNDP2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC102835 |
| GeneCard ID
| CNDP2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
