| Identification |
|---|
| BMDB Protein ID
| BMDBP00133 |
| Secondary Accession Numbers
| None |
| Name
| Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase |
| Synonyms
|
Not Available
|
| Gene Name
| ADPRM |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ADP-ribose diphosphatase activity |
| Specific Function
| Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| ADPRM |
| Gene Sequence
|
>618 bp
ATGGATTATAAGCCCGAACCTGAACTCCACAGTGAGAGCTCTGAACGTCTCTTCTCCTTT
GGAGTGATAGCAGATATTCAATATGCTGATTTGGAAGATGGCTATAATTTCCAGGGAAAC
AGAAGGAGGTACTACAGACACAGTCTTCTTCACTTACAGGGTGCTATCGAACACTGGAAT
CAAGAACGCAGCCCGCCCCGTTGTGTGCTTCAGCTTGGAGACATCATCGACGGATACAAT
GCGCAGTACAAAGCATCAGAAAAGTCACTGGAGCGCGTCATGAACACATTCCAAATGCTG
AGAGTCCCTGTTCATCACACGTGGGGAAACCACGAATTCTATAATTTCAGCAGAGACTAT
TTAACAAACTCCAAACTTAACACAAAGTTTCTGGAAGACCAGATTGCCCACCATCCTGAG
ACTGTGCCCTCGGAGGATTATTACGCGTATCATTTTGTACCATTCCCTAAATTCCGCTTC
ATTTTACTCGATGCTTATGACATGAGTGTCTTGGGCGTGGATCAGTCTTCTCCAAAATAC
CAGCAGTGTCTGAAGATACTGAGGGAGCACAACCCAAATACGGAACTGAATAGTCCTCAA
GGTGAATTATTCCTTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 337 |
| Molecular Weight
| 39235.0 |
| Theoretical pI
| 6.29 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
MDYKPEPELHSESSERLFSFGVIADIQYADLEDGYNFQGNRRRYYRHSLLHLQGAIEHWN
QERSPPRCVLQLGDIIDGYNAQYKASEKSLERVMNTFQMLRVPVHHTWGNHEFYNFSRDY
LTNSKLNTKFLEDQIAHHPETVPSEDYYAYHFVPFPKFRFILLDAYDMSVLGVDQSSPKY
QQCLKILREHNPNTELNSPQGLREPQFVQFNGGFSPEQLNWLNAVLTFSDRNQEKVVIVS
HLPIYPEASDSVCLAWNYRDALAVIWSHKCVVCFFAGHTHDGGYSEDPYGVHHVNIEGVI
ETAPDSQAFGTVHVYPDKMMLEGRGRVPHRIMNYRKE
|
| External Links |
|---|
| GenBank ID Protein
| AAI51326.1 |
| UniProtKB/Swiss-Prot ID
| A7YY53 |
| UniProtKB/Swiss-Prot Entry Name
| ADPRM_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AAFC03054081 |
| GeneCard ID
| ADPRM |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
