Showing metabocard for Glucose 1-phosphate (BMDB0001586)

General function:

Carbohydrate transport and metabolism

Specific function:

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

Gene Name:

PYGM

Uniprot ID:

B0JYK6

Molecular weight:

97288.0

General function:

Involved in glucose-6-phosphatase activity

Specific function:

Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity).

Gene Name:

G6PC

Uniprot ID:

Q29RU6

Molecular weight:

40827.0

Reactions

General function:

Carbohydrate transport and metabolism

Specific function:

This enzyme participates in both the breakdown and synthesis of glucose.

Gene Name:

PGM1

Uniprot ID:

Q08DP0

Molecular weight:

61589.0

Reactions

General function:

Energy production and conversion

Specific function:

Not Available

Gene Name:

GALT

Uniprot ID:

Q0V7N7

Molecular weight:

37812.0

General function:

Energy production and conversion

Specific function:

Not Available

Gene Name:

GALT

Uniprot ID:

Q58CX1

Molecular weight:

41288.0

Reactions

General function:

Involved in UTP:glucose-1-phosphate uridylyltransferase

Specific function:

Plays a central role as a glucosyl donor in cellular metabolic pathways.

Gene Name:

UGP2

Uniprot ID:

Q07130

Molecular weight:

56903.0

Reactions

General function:

Carbohydrate transport and metabolism

Specific function:

Glycogen phosphorylase that regulates glycogen mobilization. Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

Gene Name:

PYGB

Uniprot ID:

Q3B7M9

Molecular weight:

96340.0

General function:

Carbohydrate transport and metabolism

Specific function:

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity).

Gene Name:

PYGL

Uniprot ID:

Q0VCM4

Molecular weight:

97456.0

Reactions

General function:

Carbohydrate transport and metabolism

Specific function:

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

Gene Name:

PYGM

Uniprot ID:

P79334

Molecular weight:

97293.0

General function:

Not Available

Specific function:

Not Available

Gene Name:

PGM2L1

Uniprot ID:

A5PKH8

Molecular weight:

70419.0

Reactions

General function:

Not Available

Specific function:

Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.

Gene Name:

GALE

Uniprot ID:

Q3T105

Molecular weight:

38254.0

Reactions