| Identification |
|---|
| BMDB Protein ID
| BMDBP02797 |
| Secondary Accession Numbers
| None |
| Name
| Endothelin receptor type B |
| Synonyms
|
Not Available
|
| Gene Name
| EDNRB |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in endothelin receptor activity |
| Specific Function
| Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 12 |
| Locus
| 12q22 |
| SNPs
| EDNRB |
| Gene Sequence
|
>1326 bp
ATGCAGCCGCTGCCCAGCTTGTGCGGACGCGCCCTGGTGGCGCTGATCCTTGCCTGCGGC
GTGGCGGGGATCCAAGCAGAAGAGAGGGAATTCCCGCCAGCCGGGGCCACTCAGCCACTT
CCGGGGACCGGAGAGATGATGGAGACCCCGACTGAGACCTCCTGGCCCGGGAGGTCCAAC
GCCAGCGACCCGCGATCGTCCGCAACACCGCAGATTCCTAGAGGGGGAAGGATGGCGGGA
ATCCCACCGCGCACCCCACCCCCGTGCGATGGACCCATAGAGATCAAGGAGACTTTCAAG
TACATCAACACGGTGGTGTCCTGCCTAGTGTTCGTGCTGGGCATCATCGGAAACTCCACG
CTACTGAGAATCATTTACAAGAACAAGTGCATGCGAAACGGTCCAAATATCTTGATAGCC
AGCCTGGCTCTCGGAGACCTGCTGCACATTATCATTGATATCCCCATCAATACCTACAAG
CTGCTTGCCAAGGACTGGCCCTTTGGGGTTGAGATGTGTAAGCTGGTGCCTTTCATTCAG
AAGGCCTCCGTGGGCATCACTGTGCTGAGTCTATGTGCTCTAAGTATTGACAGATATCGA
GCTGTTGCTTCTTGGAGTCGGATTAAAGGAATCGGGGTTCCAAAATGGACAGCAGTAGAA
ATTGTTTTAATTTGGGTGGTCTCCGTGGTTCTGGCTGTCCCTGAGGCTGTGGGTTTTGAT
ATAATTACCAGTGATCACATAGGAAATAAACTGAGAATCTGCTTGCTCCATCCCACTCAG
AAAACAGCATTTATGCAGTTTTACAAGACAGCTAAAGACTGGTGGCTATTTAGTTTCTAT
TTCTGCCTGCCGCTGGCCATCACTGCATTGTTTTATACCCTGATGACTTGTGAAATGTTG
AGAAAGAAGAGTGGTATGCAAATTGCCTTAAATGATCACTTAAAACAGAGACGGGAAGTG
GCCAAAACAGTATTTTGCCTGGTCCTTGTCTTTGCTCTGTGTTGGCTTCCTCTTCATCTT
AGCAGGATTTTGAAGCTCACTCTTTATGATCAGCATGATCCCCGTAGATGTGAATTTTTA
AGCTTTTTGTTGGTATTGGACTACATTGGCATCAACATGGCCTCCCTGAATTCCTGTATT
AACCCAATAGCTCTGTATTTGGTGAGCAAAAGATTCAAAAACTGCTTTAAGTCATGTTTA
TGCTGCTGGTGCCAATCATTTGAAGAAAAACAGTCCTTGGAGGAAAAGCAGTCGTGCTTA
AAGTTCAAAGCTAACGATCACGGATATGACAACTTCCGTTCCAGTAATAAATACAGCTCA
TCTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 441 |
| Molecular Weight
| 49371.0 |
| Theoretical pI
| 8.82 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 101-125
- 137-162
- 175-196
- 218-242
- 271-295
- 324-349
- 362-388
|
| Protein Sequence
|
>Endothelin B receptor
MQPLPSLCGRALVALILACGVAGIQAEEREFPPAGATQPLPGTGEMMETPTETSWPGRSN
ASDPRSSATPQIPRGGRMAGIPPRTPPPCDGPIEIKETFKYINTVVSCLVFVLGIIGNST
LLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINTYKLLAKDWPFGVEMCKLVPFIQ
KASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAVGFD
IITSDHIGNKLRICLLHPTQKTAFMQFYKTAKDWWLFSFYFCLPLAITALFYTLMTCEML
RKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQHDPRRCEFL
SFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCL
KFKANDHGYDNFRSSNKYSSS
|
| External Links |
|---|
| GenBank ID Protein
| BAA01762.1 |
| UniProtKB/Swiss-Prot ID
| P28088 |
| UniProtKB/Swiss-Prot Entry Name
| EDNRB_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| D10994 |
| GeneCard ID
| EDNRB |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
