| Identification |
|---|
| BMDB Protein ID
| BMDBP02519 |
| Secondary Accession Numbers
| None |
| Name
| DnaJ homolog subfamily C member 24 |
| Synonyms
|
Not Available
|
| Gene Name
| DNAJC24 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Posttranslational modification, protein turnover, chaperones |
| Specific Function
| Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) (By similarity). |
| Pathways
|
- Peptidyl-diphthamide biosynthesis
- Protein modification
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 15 |
| Locus
| Not Available |
| SNPs
| DNAJC24 |
| Gene Sequence
|
>450 bp
ATGATGGCGTTTGAGCAGATACCAAAAAAGGATTGGTACAGCATTCTGGGAGCAGACCCA
TCTGCAAGTGTATCAGACCTAAAACAAAAGTATCAAAAACTCATTTTAATGTATCATCCA
GATAAACAGAGTGCAGATGCGCCAGCAGGATCAGTGGAGGAATGTATACAGAAGTTCATT
GAAATTGATCAGGCATGGAAAATTCTAGGGAATGAAGAAACAAAAAAAGAGTATGACCTG
CAGCGACATGAAGATGATCTAAGAAATATGGGACCAGTAGATGCTCGAATATATCTTGAA
GAAATGTCTTGGAATGAAGATGATCATTCCTTTTCTCTGAGCTGTCGATGTGGTGGAAAA
TACAGTGTTTCAAAGGATGAAGCAGAAGAAGTTACACTGATTTCTTGTGATACATGTTCA
CTAATTATCGAACTCCTTCATTATTGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 149 |
| Molecular Weight
| 17135.0 |
| Theoretical pI
| 4.36 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>DnaJ homolog subfamily C member 24
MAFEQIPKKDWYSILGADPSASVSDLKQKYQKLILMYHPDKQSADAPAGSVEECIQKFIE
IDQAWKILGNEETKKEYDLQRHEDDLRNMGPVDARIYLEEMSWNEDDHSFSLSCRCGGKY
SVSKDEAEEVTLISCDTCSLIIELLHYC
|
| External Links |
|---|
| GenBank ID Protein
| AAI20443.1 |
| UniProtKB/Swiss-Prot ID
| Q0VBY7 |
| UniProtKB/Swiss-Prot Entry Name
| DJC24_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC120442 |
| GeneCard ID
| DNAJC24 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
