1.0 2018-05-07 22:31:05 UTC 2020-05-20 21:02:22 UTC BMDBP02332 Enzyme ZNF274 Involved in transcription factor activity Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. The SETDB1-TRIM28-ZNF274 complex may play a role in recruiting ATRX to the 3'-exons of zinc-finger coding genes with atypical chromatin signatures to establish or maintain/protect H3K9me3 at these transcriptionally active regions (By similarity). BMDB0001303 Zinc 18 >1863 bp ATGGCCTCCGGGCTTCCGACGGATTGGTTCCGTGAACCAGTGACCTTTGAAGATGTGGCC TTGGGTTTTACCCCAGATGAGTGGGGAAAGCTGGACCTCGAACAGAAGTCCCTGTACAGG GAGGTGATGCTGGAGAACTACAGGAACCTGGTCTCAGTGGAACATCAGCTTTCCAAGCCA GATGTGGTATCTCAGTTAGAGGAAGAGGAAGAGCTGTGGTCGGTGGAGAGAGGAATTCCT CAAGACACCTTTTCAGAGTGTCCTGAGGCTCAGTTGGAACCTCAGTTGGATCCTTTTCCT GCTGGGAATCCCCTGATGAACATCGAGGTGGTTGAAGTCCTCACCCTGAACCAGGAGGTG GCTGTTCCCCGGAATGCCCAGATCCGGGCTCTGTATGCTGAAGATGAGGGCCTGAGCCCA GAGGTTCTCAGGGAGCCCCCTCAACATCTGGATAAGCCTACGGCTGATCCTGAGATGGCT CGGCAGAGGTTCCGGGGTTTCCACTTTGAGGAGGTGGCTGGTCCCCGCGAGGCGCTGGCC CAACTCCGGGAGCTCTGCTGCCAGTGGCTGCGGCCCGAGGCGCACTCCAAGGACCAGATG CTGGAGCTGCTGGTGCTGGAGCAGTTCCTGGGCGCACTGCCTGAGAAGCTGCGGCTATGG GTGGAGTCGCAGCACCCAGTGGACTGCCGGCAGGCAGTGGCCCTGGTGGAGGACGTGACC TGGATCTCTGAGGAGGAAACACTGCCCACCCAGGGCGCCCCCGGCACTCTCCCTCCCGCG GCTCAGCAGGACACAGCTACCTGGCCCGTGAAGGCGCTGCCTGAGGATCCAGTGACCTTC CTGGACGTGGCTGTGGACTTCAGCACGGAGGAGTGGGGGCTGCTGGACCCAACACAGCGG ACTGAGTACCACGACGTGATGCTGGAGACCTTCGGACACCTGGTGTCTGTGGGGTGGGAG ACGACCCTGGACAGCAAGCAGTTAACGCCACAGCCTGGACCTCCTGAGGAGGGGCCCGCC TGCCCCCTGAAGGAGGAGGAGGGGTCCTCGGCGGATGACGCCCGGCCCTCCACCTCCGGA GAGGCTCTGGAGGCCGGGGCCCCGGGAGTCTGGGACACAGCGCTGAAACCGGTGACACTC GCTTCGGAAAATACCCTCCCCCCGCAGCCGCCCGGGGACAGCCCCCAACCCCAGGCGAGC ACAGGCCCGGACCGCGGCCGCGTCTCCCTTCAGAAAGCTGTTCCTAGAAAGCGCTTGCGC AAGCGCGACCCCTGGCTTAAAAGGGGGACACGCGGCGCATGCGTAAAGCTTCCTCCAAAG CGCGGCGGCGCCGGGAAGGCTGTGGAGAGCGGCGGCGACGGGGGCAGGAGGCCCTGCGCC CGGAACGCCCCGCAGATCACCTTCACGCGAATTCACAAAGGGAGCCAGGTGTGCCGGTGC AGCGAATGCGGGAAGACGTTCCGGAATCCCAGGTACTTCTCGGTGCACAAGAAGATCCAC ACGGGAGAGAAGCCCTATGTGTGTCGGGACTGCGGGAAGGCGTTCGTGCAGAGCTCCTCC CTCAGGCAGCACCAGAGGGTTCACACTGGGGAGAGACCCTTCGTGTGTCACGAGTGCGGG AGGACTTTCAACGACCGCTCGGCCATCTCCCAGCACCTGCGGACCCACACCGGGGCCAAG CCCTACCCGTGTCCGGACTGCGGCAAAGCCTTCCGCCAGAGCTCCCATCTCATCCGGCAT CAGAGGACTCACACCGGCGAGCGCCCCTACTCCTGTAGCAAGTGCGGAAAGGCCTTCACG CAGAGCTCGCACCTGATAGGGCACCAGAAAACGCACAGCAGGGTGAAATGCAAGAAGAAA TAG 620 69254.0 6.55 None >ZNF274 protein MASGLPTDWFREPVTFEDVALGFTPDEWGKLDLEQKSLYREVMLENYRNLVSVEHQLSKP DVVSQLEEEEELWSVERGIPQDTFSECPEAQLEPQLDPFPAGNPLMNIEVVEVLTLNQEV AVPRNAQIRALYAEDEGLSPEVLREPPQHLDKPTADPEMARQRFRGFHFEEVAGPREALA QLRELCCQWLRPEAHSKDQMLELLVLEQFLGALPEKLRLWVESQHPVDCRQAVALVEDVT WISEEETLPTQGAPGTLPPAAQQDTATWPVKALPEDPVTFLDVAVDFSTEEWGLLDPTQR TEYHDVMLETFGHLVSVGWETTLDSKQLTPQPGPPEEGPACPLKEEEGSSADDARPSTSG EALEAGAPGVWDTALKPVTLASENTLPPQPPGDSPQPQASTGPDRGRVSLQKAVPRKRLR KRDPWLKRGTRGACVKLPPKRGGAGKAVESGGDGGRRPCARNAPQITFTRIHKGSQVCRC SECGKTFRNPRYFSVHKKIHTGEKPYVCRDCGKAFVQSSSLRQHQRVHTGERPFVCHECG RTFNDRSAISQHLRTHTGAKPYPCPDCGKAFRQSSHLIRHQRTHTGERPYSCSKCGKAFT QSSHLIGHQKTHSRVKCKKK AAI49475.1 A6QPT6 ZN274_BOVIN BC149474 ZNF274