| Identification |
|---|
| BMDB Protein ID
| BMDBP02287 |
| Secondary Accession Numbers
| None |
| Name
| Vesicular glutamate transporter 2 |
| Synonyms
|
Not Available
|
| Gene Name
| SLC17A6 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate (By similarity). |
| Pathways
|
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 29 |
| Locus
| Not Available |
| SNPs
| SLC17A6 |
| Gene Sequence
|
>1749 bp
ATGGAGTCGGTAAAACAAAGGATTTTGACCCCAGGAAAAGAGGGGCTAAAGAATTTTGCT
GGAAAATCCCTCGGCCAGATCTACAGGGTGCTGGAGAAGAAGCAGGACGCCGGGGAGACC
ATCGAGCTGACGGAGGATGGCAAGCCCCTGGAGGTGCCTGAGAAGAAGGCGCCGCTGTGC
GACTGCACGTGCTTTGGCCTGCCGCGTCGCTACATCATCGCCATCATGAGCGGCCTGGGC
TTCTGCATCTCCTTCGGCATCCGCTGCAACCTGGGCGTGGCCATCGTGGACATGGTCAAC
AACAGCACCATCCACCGCGGGGGCAAGGTGATCAAGGAGAAAGCCAAATTCAACTGGGAC
CCGGAAACCGTAGGGATGATCCACGGTTCTTTCTTTTGGGGCTATATCATCACACAGATT
CCAGGCGGCTACATCGCTTCTCGGCTGGCAGCCAACAGAGTTTTCGGAGCTGCCATACTT
CTTACCTCTACCCTGAATATGCTAATCCCATCAGCAGCCAGAGTGCATTATGGGTGTGTC
ATCTTTGTTAGGATACTGCAGGGACTTGTTGAGGGTGTCACCTACCCAGCATGTCATGGG
ATATGGAGCAAATGGGCTCCCCCTTTAGAGAGGAGTCGATTGGCAACCACCTCCTTTTGT
GGTTCCTATGCTGGAGCTGTGATTGCAATGCCTTTAGCTGGCATTCTTGTGCAGTATACT
GGCTGGTCTTCCGTATTCTATGTCTATGGAAGCTTTGGAATGATCTGGTACATGTTTTGG
CTTTTGGTGTCCTACGAGAGTCCTGCAAAGCATCCTACTATTACAGATGAAGAACGTAGG
TACATAGAAGAAAGCATTGGAGAGAGTGCAAATCTTTTAGGTGCAATGGAAAAATTCAAG
ACTCCATGGAGAAAATTTTTTACATCTATGCCAGTCTATGCAATAATTGTTGCAAACTTC
TGCAGAAGCTGGACTTTTTATTTATTGCTTATTAGTCAGCCAGCATATTTTGAGGAAGTC
TTTGGATTTGAAATCAGCAAGGTTGGCATGCTATCTGCTGTGCCACACTTAGTAATGACA
ATTATTGTACCTATTGGAGGGCAGATTGCAGATTTTCTAAGAAGCAAACAAATTCTTTCA
ACTACTACAGTAAGGAAGATCATGAATTGTGGTGGTTTTGGCATGGAGGCCACGCTGCTT
CTGGTTGTTGGTTATTCTCACACTAGAGGGGTCGCAATCTCATTCTTGGTACTTGCCGTG
GGATTCAGTGGATTTGCTATTTCTGGCTTCAATGTCAACCACTTGGATATTGCTCCAAGA
TATGCCAGTATCTTAATGGGCATTTCGAATGGTGTTGGCACATTGTCAGGAATGGTTTGC
CCTATTATTGTTGGTGCAATGACAAAGAATAAGTCACGTGAAGAGTGGCAGTATGTCTTC
CTGATCGCTGCCCTAGTCCACTATGGTGGAGTTATATTTTATGCAATATTTGCCTCAGGA
GAGAAGCAGCCCTGGGCAGACCCTGAGGAAACAAGTGAAGAGAAATGTGGATTTATCCAT
GAAGATGAGCTCGATGAAGAAACAGGGGACATTACTCAAAATTATATAAATTATGGTACC
ACTAAGTCTTACGGTGCCACAACACAGGCCAATGGAGGTTGGCCCAATGGTTGGGAAAAG
AAAGAGGAATTTGTACAAGAAGAAGTACAAAACTCATACAACTATAAGGACCGAGATGAT
TATTCATAA
|
| Protein Properties |
|---|
| Number of Residues
| 582 |
| Molecular Weight
| 64546.0 |
| Theoretical pI
| 6.83 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 72-92
- 126-146
- 149-169
- 178-198
- 217-237
- 245-265
- 311-331
- 350-370
- 387-407
- 410-430
- 444-464
- 478-498
|
| Protein Sequence
|
>Vesicular glutamate transporter 2
MESVKQRILTPGKEGLKNFAGKSLGQIYRVLEKKQDAGETIELTEDGKPLEVPEKKAPLC
DCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWD
PETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCV
IFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT
GWSSVFYVYGSFGMIWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFK
TPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMT
IIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAV
GFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVF
LIAALVHYGGVIFYAIFASGEKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGT
TKSYGATTQANGGWPNGWEKKEEFVQEEVQNSYNYKDRDDYS
|
| External Links |
|---|
| GenBank ID Protein
| AAI47974.1 |
| UniProtKB/Swiss-Prot ID
| A6QLI1 |
| UniProtKB/Swiss-Prot Entry Name
| VGLU2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC147973 |
| GeneCard ID
| SLC17A6 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
