<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <version>1.0</version>
  <creation_date>2018-05-07 22:30:52 UTC</creation_date>
  <update_date>2020-05-20 21:05:56 UTC</update_date>
  <accession>BMDBP02285</accession>
  <secondary_accessions>
  </secondary_accessions>
  <protein_type>Enzyme</protein_type>
  <synonyms>
  </synonyms>
  <gene_name>SLC5A3</gene_name>
  <general_function>Involved in sodium ion binding</general_function>
  <specific_function>Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function.</specific_function>
  <pathways>
  </pathways>
  <metabolite_associations>
    <metabolite>
      <accession>BMDB0000588</accession>
      <name>Sodium</name>
    </metabolite>
  </metabolite_associations>
  <go_classifications>
  </go_classifications>
  <subcellular_locations>
  </subcellular_locations>
  <gene_properties>
    <chromosome_location/>
    <locus/>
    <gene_sequence/>
  </gene_properties>
  <protein_properties>
    <residue_number>718</residue_number>
    <molecular_weight>79674.0</molecular_weight>
    <theoretical_pi>7.55</theoretical_pi>
    <pfams>
    </pfams>
    <transmembrane_regions>
      <region>10-29</region>
      <region>39-57</region>
      <region>87-110</region>
      <region>124-144</region>
      <region>158-183</region>
      <region>187-205</region>
      <region>304-324</region>
      <region>354-376</region>
      <region>407-430</region>
      <region>444-462</region>
      <region>511-532</region>
      <region>696-716</region>
    </transmembrane_regions>
    <signal_regions>
      <region>None</region>
    </signal_regions>
    <polypeptide_sequence>&gt;Sodium/myo-inositol cotransporter
MRAVLETADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNI
GSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGH
RIQVYFAALSLILYIFTKLSVDLYSGALFIQESMGWNLYVSVILLIGMTALLTVTGGLVA
VIYTDTLQALLMIVGALTLMVISMMEIGGFEEVKRRYMLASPNVTSILLTYNLSNTNSCN
VHPKKDALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTL
MAGFLKLLPMFIIVVPGMISRILFADDIACINPEHCMQVCGSRAGCSNIAYPRLVMKLVP
VGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVV
ISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFIL
VVVRLTLAFAYRAPECDQPDNRPVFIKDIHYMYVATALFWITGLITVIVSLLTPPPTKEQ
IRTTTFWSKKSLVVKESCSPKDEPYKMQEKSILRCSENSEVINHVIPNGKSEDSIKGLQP
EDVNLLVTCREEGNPVASLGHSEAETPVDAYSNGQAALMGEKERKKEAEDGSRYWKFIDW
FCGFKSKSLSKRSLRDLMEEEAVCLQMLEEPPQVKVILNIGLFGVCSLGIFMFVYFSL</polypeptide_sequence>
  </protein_properties>
  <genbank_protein_id>AAA93188.1</genbank_protein_id>
  <uniprot_id>P53793</uniprot_id>
  <uniprot_name>SC5A3_BOVIN</uniprot_name>
  <pdb_ids>
  </pdb_ids>
  <genbank_gene_id>U41338</genbank_gene_id>
  <genecard_id>SLC5A3</genecard_id>
  <geneatlas_id/>
  <general_references>
  </general_references>
  <metabolite_references>
  </metabolite_references>
</protein>
