| Identification |
|---|
| BMDB Protein ID
| BMDBP02269 |
| Secondary Accession Numbers
| None |
| Name
| Sodium/hydrogen exchanger 1 |
| Synonyms
|
Not Available
|
| Gene Name
| SLC9A1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Inorganic ion transport and metabolism |
| Specific Function
| Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| Not Available |
| SNPs
| SLC9A1 |
| Gene Sequence
|
>2454 bp
ATGCTTCTGTGGCCTGGCGCCAGTGGCCTCCCTCCGCCTCGAATCTTCCCTTCGTTGCTT
GTGGTGGTAGCCTTGGTGGGGCTGCTACCCGTTCTCAGAAGCTATGGCCTCCAGATCAGC
CCTACCGCCAGCACCATCAGAGGCTCAGAGCCGCCCCGGGAACGCTCAATTGGGGATGTC
ACCACCGCCCCACCGGAGCTCGCCCCCGAGAGCCGCCCTGTTAACCATTCCTTCGCTGAA
CATAGCCCAAAGGCTCGAAAGGCCTTTCCAGTCCTGGGCATCGACTACCAACACGTGCGC
ATACCCTTCGAAATCGCCCTCTGGATCCTACTGGCCTGCCTCATGAAGATAGGTTTCCAC
GTGATCCCCACCATCTCGAGCATCGTCCCGGAGAGCTGCCTGCTGATTGTGGTGGGGCTG
CTGGTGGGGGGTCTGATCAAGGGCGTGGGCGAGACGCCCCCCATCCTGCAGTCGGAAGTC
TTCTTCCTCTTCCTGCTGCCGCCCATCATCCTGGATGCTGGCTACTTCCTGCCGCTGCGG
CAGTTCACGGAGAACCTGGGCACCATCCTGATCTTCGCCGTGGTGGGCACGCTGTGGAAC
GCCTTCTTCCTGGGTGGCCTCATGTACGCCGTGTGCCTGGTGGGTGGCGAGCAGATCAAC
AACATCGGCCTTCTGGAGAACCTGCTGTTCGGCAGCATCATCTCGGCCGTGGACCCCGTG
GCCGTGCTGGCCGTCTTCGAGGAGATTCACATCAACGAGCTGCTCCACATCCTTGTGTTT
GGGGAGTCCCTGCTCAATGACGCCGTCACTGTGGTCCTGTATCACCTCTTTGAGGAGTTT
GCCAACTACGACCGCGTGGGCATCGTGGACATCATCCTCGGCTTCCTGAGCTTCTTCGTG
GTGTCCCTGGGTGGGGTGTTCGTGGGCGTGGTCTACGGGGTCATTGCAGCCTTCACCTCC
CGCTTCACCTCCCACATCCGCGTCATCGAGCCGCTCTTCGTCTTCCTCTACAGCTACATG
GCCTACCTGTCGGCCGAGCTCTTCCACCTGTCAGGCATCATGGCACTCATTGCCTCGGGC
GTGGTGATGCGCCCCTACGTGGAAGCCAACATCTCCCACAAGTCCCACACGACCATCAAG
TATTTCCTCAAAATGTGGAGCAGCGTCAGTGAAACCCTCATCTTCATCTTCCTGGGCGTC
TCCACTGTGGCCGGCTCCCACCACTGGAACTGGACGTTTGTCATCAGCACCCTGCTCTTC
TGCCTCATCGCCCGAGTGCTGGGGGTGCTGGGCCTGACCTGGTTCATCAACAAGTTCCGC
ATTGTGAAGTTGACCCCCAAGGACCAGTTCATCATTGCCTACGGGGGCCTGCGAGGGGCC
ATCGCCTTCTCCCTGGGCTACCTCCTGGACAAGAAGCACTTCCCTATGTGTGACCTGTTC
CTCACGGCCATCATCACCGTCATCTTTTTCACCGTCTTTGTGCAGGGCATGACCATTCGG
CCCCTGGTAGACCTGCTGGCTGTGAAGAAAAAGCAAGAAACGAAGCGTTCTATCAACGAG
GAGATCCACACGCAGTTCCTGGACCACCTTCTGACAGGCATCGAGGACATCTGTGGTCAT
TACGGCCACCACCACTGGAAAGACAAGCTCAACCGGTTTAATAAGAAGTACGTGAAGAAG
TGTCTGATAGCCGGTGAGCGCTCCAAGGAGCCCCAGCTCATCGCTTTCTACCACAAGATG
GAGATGAAGCAAGCTATCGAGCTGGTGGAAAGTGGAGGCATGGGCAAGATCCCCTCGGCC
GTCTCCACCGTCTCCATGCAGAACATCCACCCCAAGTCCCTGCCGGCCGAGCGCATCCTG
CCAGCACTGTCCAAGGACAAGGAAGAGGAGATCCGCAAAATCCTGAGGAACAACTTGCAG
AAGACCAGGCAGCGGCTGCGGTCCTACAACAGACACACGCTGGTGGCCGACCCCTACGAG
GAGGCCTGGAACCAGATGCTGCTCCGGAGACAGAAGGCCAGGCAACTGGAGCAGAAGATC
AGCAACTACCTGACCGTGCCGGCCCACAAGCTGGACTCGCCCACCATGTCTCGGGCCCGC
ATCGGCTCAGACCCACTGGCCTATGAGCCCAAGGCCGACTTGCCTGTGATCACCATCGAC
CCGGCCTCCCCGCAGTCGCCTGAGTCTGTGGACCTGGTGAACGAGGAGCTGAAGGGCAAG
GTCCTGGGGCTGAGCCGGGATCCCGGAAGGCTGGCTGAGGAGGAGGAGGACGACAACGGA
CCCCGATGGCTTACGATGCGGACCAAGGAGCCCTCATCCCCGGGCACCGACGATGTTTTC
ACCCCGGCACCGAGCGACAGCCCCAGCTCTCAGAGGATACAGCGCTGCCTCAGTGACCCA
GGCCCCCACCCCGAGCCTGGGGAGGGAGAGCCTTTCATCCCCAAGGGCCAGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 817 |
| Molecular Weight
| 91017.0 |
| Theoretical pI
| 7.57 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 12-32
- 105-127
- 130-149
- 155-174
- 192-211
- 228-247
- 257-276
- 295-315
- 339-358
- 411-430
- 449-470
- 480-499
|
| Protein Sequence
|
>Sodium/hydrogen exchanger 1
MLLWPGASGLPPPRIFPSLLVVVALVGLLPVLRSYGLQISPTASTIRGSEPPRERSIGDV
TTAPPELAPESRPVNHSFAEHSPKARKAFPVLGIDYQHVRIPFEIALWILLACLMKIGFH
VIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPILQSEVFFLFLLPPIILDAGYFLPLR
QFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLENLLFGSIISAVDPV
AVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYDRVGIVDIILGFLSFFV
VSLGGVFVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASG
VVMRPYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLF
CLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLF
LTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGH
YGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSA
VSTVSMQNIHPKSLPAERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYE
EAWNQMLLRRQKARQLEQKISNYLTVPAHKLDSPTMSRARIGSDPLAYEPKADLPVITID
PASPQSPESVDLVNEELKGKVLGLSRDPGRLAEEEEDDNGPRWLTMRTKEPSSPGTDDVF
TPAPSDSPSSQRIQRCLSDPGPHPEPGEGEPFIPKGQ
|
| External Links |
|---|
| GenBank ID Protein
| AAA91483.1 |
| UniProtKB/Swiss-Prot ID
| Q28036 |
| UniProtKB/Swiss-Prot Entry Name
| SL9A1_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| U49432 |
| GeneCard ID
| SLC9A1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
