| Identification |
|---|
| BMDB Protein ID
| BMDBP01583 |
| Secondary Accession Numbers
| None |
| Name
| Molybdenum cofactor biosynthesis protein 1 |
| Synonyms
|
Not Available
|
| Gene Name
| MOCS1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Coenzyme transport and metabolism |
| Specific Function
| Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). MOCS1A catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and MOCS1B catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cPMP. |
| Pathways
|
- Cofactor biosynthesis
- Molybdopterin biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 23 |
| Locus
| Not Available |
| SNPs
| MOCS1 |
| Gene Sequence
|
>1149 bp
ATGGCGGCCCAGCCAGTGTCCCGGGTGGTGCGGCGGGTCCTGAGAGCCGGTGTCCGGAGC
TGCAGCTCGGGGGCTCCGGTGACGCAGCCATGCCCTGGGGAGCCTGTCGTGGAGGTGCTG
TCCAGGCCGAGGCCATTCCTGGGGGAGCACGCCGCCCCCTTCTCCGCCTTCCTCACCGAC
AGCTTCGGCCGGCGCCACAGCTATCTGCGGATCTCCCTCACCGAGAGGTGTAACCTCAGA
TGTCAATACTGCATGCCTGAGGAGGGGGTCCCTCTGACCCCCAAGGCTGACCTGCTGACC
ACAGAGGAAATCCTGACCCTGGCCCGGCTCTTTGTGAAAGAAGGTGTGGACAAGATCCGG
CTCACGGGTGGGGAGCCGCTCATCCGGCCGGACGTGGTGGACATTGTGGCCCAGCTCCGC
CAGCTGGAAGGCCTGAGGACCATCGGCATCACCACCAACGGCATCAACCTAGCCCGGCTG
CTACCTCAGCTCCAGAAAGCTGGTCTCAGCGCCATCAACATCAGCCTGGACACGCTGGTA
CCAGCCAAGTTTGAGTTCATCGTCCGCAGGAAAGGCTTCCACAAGGTCATGGAGGGCATC
CACAAGGCCATCGAGCTGGGCTACAGCCCCGTGAAGGTGAACTGCGTGGTGATGCGAGGC
CTGAACGAGGACGAACTCCTGGACTTTGTGGCCTTGACCGAGGGCCTCCCCCTGGACGTG
CGCTTCATTGAGTACATGCCCTTTGACGGCAACAAGTGGAACTTTAAGAAGATGGTCAGC
TATAAGGAGATGCTGGACACCCTCCGGCAGCAGTGGCCAGAGCTGGAGAAGCTGCCCGAG
GAAGAATCCAGCACAGCCAAGGCCTTTAAAATCCCCGGTTTCCGAGGCCAGGTCAGCTTC
ATCACGTCTATGTCTGAGCATTTCTGTGGGACCTGCAACCGGCTGCGAATCACAGCTGAC
GGGAACCTCAAGGTCTGCCTCTTCGGGAACTCAGAGGTGTCTCTACGGGATCACCTGCGG
GCAGGGGCCTCCGAGGAGGAGCTGCTGAGGGTCATCGGGGCTGCGGTGGGCAGGAAGAAG
CGGCAGCACGCAGGCATGTTCAATATCTCCCAGATGAAGAACCGGCCCATGATCCTCATC
GGTGGGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 633 |
| Molecular Weight
| 69659.0 |
| Theoretical pI
| 9.33 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Molybdenum cofactor biosynthesis protein 1
MAAQPVSRVVRRVLRAGVRSCSSGAPVTQPCPGEPVVEVLSRPRPFLGEHAAPFSAFLTD
SFGRHHSYLRISLTERCNLRCQYCMPEEGVPLTPKADLLTTEEILTLARLFVKEGVDKIR
LTGGEPLIRPDVVDIVAQLRQLEGLRTIGITTNGINLARLLPQLQKAGLSAINISLDTLV
PAKFEFIVRRKGFHKVMEGIHKAIELGYSPVKVNCVVMRGLNEDELLDFVALTEGLPLDV
RFIEYMPFDGNKWNFKKMVSYKEMLDTLRQQWPELEKLPEEESSTAKAFKIPGFRGQVSF
ITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLRAGASEEELLRVIGAAVGRKK
RQHAGMFNISQMKNRPMILIELFLMRQDSPPALPSTFRNSLRVQVLRHRVSFSSQMVTLW
KGGGVPQAPLVAQRWLGSSLPQRHFSSHLDSDANPKCLSPTEPQAPAASSGPLPDSDQLT
HVDTEGRMAMVDVGRKPDTERVAVASAVVLLGPVAFKLIQENQLKKGDALAVAQLAGIQA
AKLTSQLIPLCHHVALSHVQVQLELDRTRHAAVIQASCRARGPTGVEMEALTSAAVAALA
LYDMCKAVSRDIVLAEIKLVSKTGGQRGDFHRT
|
| External Links |
|---|
| GenBank ID Protein
| AAX46428.1 |
| UniProtKB/Swiss-Prot ID
| Q1JQD7 |
| UniProtKB/Swiss-Prot Entry Name
| MOCS1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT021581 |
| GeneCard ID
| MOCS1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
