| Identification |
|---|
| BMDB Protein ID
| BMDBP01121 |
| Secondary Accession Numbers
| None |
| Name
| DNA polymerase subunit gamma-2, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| POLG2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Translation, ribosomal structure and biogenesis |
| Specific Function
| Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. Binds to ss-DNA (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| POLG2 |
| Gene Sequence
|
>1458 bp
ATGCGCTCTGCTCCAGCCATCAGAGCTTGCCAGAGAATCTGCCGGTGCCTGTTGTCTGGG
TTTGGGGGTCAAGTAGATGGGAGGCAGCCGGAGCAGTTGTCGAAAGGGACAGGCTCCTTC
GTAGGGCCCGTGAGGTCGCAAGCGGAGCTACCCCGAAACGAGCCGAGAGAGGCCCCCGAG
TCTGGTGGTGAGGGGAGTGAGCCGCTGGTAGAGATCTGTCGGAAGAGACGTTTCCTCAGT
GGCACCAAGCAGCAGCTTAGCCGAGATTCTCTTCTAAACGGATGCCACCCCGGCCTTGGC
CCCTTGGGCATAGAGTTGCGGAAGAACCTGGCGGCCGAATGGTGGTCCTCAGTGGTGGTG
TTCAGGGAGCAGGTGTTCCCGGTAGACGCCCTCCATCGTGAACCAGGTCCTTCGCTGCCG
GTGGACAATGGCTTCAGGTTAGTTTCTGCAGAAACACTGCGCGAAATCTTGCAAGACAAA
GAGCTGAGTAAGGAACAGCTAGTAGCATTTCTTGAGAACTTACTAAACACTTCTGGGAAA
CTACGGGAGAACCTTCTTCACGGTGCCTTGGAGCACTATGTTAGTTACCTGGATCTGGTA
AACAAGAGGCTACCTTTTGGCCTTGCTCAGATTGGAGCGTGTTTTCACCCTGTTTCTGAT
ACTAAGCAGACACCTGATGGTGTTAAAAGAATCGGTGAAAAGACTGAAGCTTCTCTGGTA
TGGTTTACTTCAGCAAGAACTGCAAGCCAGTGGCTTGATTTCTGGTTACGTCATCGACTC
CTATGGTGGAGAAAGTTTGCTATGAGTCCATCTAACTTCAGCAGTGGAGATTGTCAGGAT
GAAGCAGGCCGAAAAGGAAACAGACTTTACTACAATTTCCCCTGGGGAAAGGAGCCAATA
GAAACCCTGTGGAACCTAGGAGATCATGAACTTTTACACATGTATCCTGGAAGTGTGGCT
CAAGTACACGGCCGAGATGGGCGGAAAAATGTGGTTCCTTCTGTTTTATCTATAAATGGA
GATCTAGACCGAGGCATGCTGGCCTACCTCTATGATTCTTTCCAGCTAACAGAGAACTCC
TTTACAAGAAAGAAAGATCTTCATAGAAAGGTGCTTAAACTTCACCCTTGCTTGGCGCCT
ATTAAAGCTGCTTTGGATGTGGGACGAGGCCCAACAGTGGAACTAAGACAGGTTTGTCAA
GGGCTGTTTAATGAATTACTGGAGAATGGAATTTCTGTGTGGCCTGGTTATCTGGAAACT
GTGCAGTCTTCACTGGAACAACTTTATTCAAAATATGATGAAATGAGTATCCTCTTCACA
GTGTTGATTACTGAAGCTACTTTGGAGAATGGATTAATACAGTTGAGAAGCAGAGACACC
ACAATGAAGGAGATGATGCATATATCCAAAGTAAAAGACTTTTTAACTAAATATATATCA
TCAGCTAAGAATGTATAG
|
| Protein Properties |
|---|
| Number of Residues
| 485 |
| Molecular Weight
| 54663.0 |
| Theoretical pI
| 8.47 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>DNA polymerase subunit gamma-2, mitochondrial
MRSAPAIRACQRICRCLLSGFGGQVDGRQPEQLSKGTGSFVGPVRSQAELPRNEPREAPE
SGGEGSEPLVEICRKRRFLSGTKQQLSRDSLLNGCHPGLGPLGIELRKNLAAEWWSSVVV
FREQVFPVDALHREPGPSLPVDNGFRLVSAETLREILQDKELSKEQLVAFLENLLNTSGK
LRENLLHGALEHYVSYLDLVNKRLPFGLAQIGACFHPVSDTKQTPDGVKRIGEKTEASLV
WFTSARTASQWLDFWLRHRLLWWRKFAMSPSNFSSGDCQDEAGRKGNRLYYNFPWGKEPI
ETLWNLGDHELLHMYPGSVAQVHGRDGRKNVVPSVLSINGDLDRGMLAYLYDSFQLTENS
FTRKKDLHRKVLKLHPCLAPIKAALDVGRGPTVELRQVCQGLFNELLENGISVWPGYLET
VQSSLEQLYSKYDEMSILFTVLITEATLENGLIQLRSRDTTMKEMMHISKVKDFLTKYIS
SAKNV
|
| External Links |
|---|
| GenBank ID Protein
| AAI20381.1 |
| UniProtKB/Swiss-Prot ID
| Q0VC30 |
| UniProtKB/Swiss-Prot Entry Name
| DPOG2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC120380 |
| GeneCard ID
| POLG2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
