| Identification |
|---|
| BMDB Protein ID
| BMDBP01009 |
| Secondary Accession Numbers
| None |
| Name
| 3-hydroxybutyrate dehydrogenase type 2 |
| Synonyms
|
Not Available
|
| Gene Name
| BDH2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron assimilation and homeostasis. Plays a role in susceptibility to bacterial infection by providing an assimilable source of iron that is exploited by pathogenic bacteria (By similarity). Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity). |
| Pathways
|
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| Not Available |
| SNPs
| BDH2 |
| Gene Sequence
|
>738 bp
ATGGGTCGACTTGATGGGAAGGTCATTGTCCTGACGGCTGCTGCTCAGGGGATCGGCCGG
GCAGCCGCATTGGCTTTTGCAAAAGAAGGTGCCAAAGTCATAGCCACCGATATCAATGAC
TCCAAACTTCAGGAACTGGATAAGTACCCAGGTATTCACACTCGGGTCCTTGATGTCACA
AAGAAGAAGCAAATTGACCAGTTTGCCAATGACATTGAGAGACTTGATGTTCTCTTTAAC
GTTGCTGGTTTCGTCCATCACGGAACCATCCTGGACTGTGAAGAGACAGACTGGGACTTC
TCGATGAACCTCAACGTCCGCAGCATGTACCTGATGATCAAGGCTTTTCTTCCTAAGATG
ATGGCTCAGAAATCTGGCAACATTATCAACATGTCCTCTGTGGCTTCCAGCATCAAAGGC
GTTGTGAACAGGTGCGTGTACAGCACAACCAAGGCGGCCGTGATCGGCCTCACAAAGTCC
GTGGCTGCAGACTTCATCCAGCAGGGTATCCGGTGCAACTGTGTGTGTCCAGGAACAGTT
GATACCCCATCTCTGCAAGAAAGAATACAAGCCAGACCAAATCCTGAAGAGGCACTGAGC
GATTTCCTAAAGAGACAGAAAACAGGAAGATTTGCAACTGCAGAAGAAGTAGCCCTGCTC
TGCGTGTACTTGGCCTCTGATGAATCTGCCTACATCACGGGGAATCCTGTCATCATTGAT
GGAGGCTGGAGTTTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 245 |
| Molecular Weight
| 26662.0 |
| Theoretical pI
| 7.3 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>3-hydroxybutyrate dehydrogenase type 2
MGRLDGKVIVLTAAAQGIGRAAALAFAKEGAKVIATDINDSKLQELDKYPGIHTRVLDVT
KKKQIDQFANDIERLDVLFNVAGFVHHGTILDCEETDWDFSMNLNVRSMYLMIKAFLPKM
MAQKSGNIINMSSVASSIKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV
DTPSLQERIQARPNPEEALSDFLKRQKTGRFATAEEVALLCVYLASDESAYITGNPVIID
GGWSL
|
| External Links |
|---|
| GenBank ID Protein
| AAI02568.1 |
| UniProtKB/Swiss-Prot ID
| Q3T046 |
| UniProtKB/Swiss-Prot Entry Name
| BDH2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC102567 |
| GeneCard ID
| BDH2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
