| Identification |
|---|
| BMDB Protein ID
| BMDBP01004 |
| Secondary Accession Numbers
| None |
| Name
| Uridine 5'-monophosphate synthase |
| Synonyms
|
Not Available
|
| Gene Name
| UMPS |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Nucleotide transport and metabolism |
| Specific Function
| Orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate |
| Pathways
|
- Pyrimidine Metabolism
- UMP biosynthesis via de novo pathway
- UMP from orotate: step 1/2.
- UMP from orotate: step 2/2
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 1 |
| Locus
| 1q31-q36 |
| SNPs
| UMPS |
| Gene Sequence
|
>1443 bp
ATGGCGGCGGCTGATGCCCTTTTGGGGTCATTGGTAACGGGTCTGTACGATGTGCAGGCT
TTTAAGTTTGGGAACTTCGTGCTGAAGAGTGGGCTCTCTTCCCCCGTGTACATCGATCTG
CGGGGCATCATATCTCGACCGAGTATTCTGAATCAGGTTGCAGAAATGTTATTTCAAACT
GCCGAAAATGCAGAGATCAATTTTGACACTGTGTGTGGAGTACCTTATACAGCTTTACCA
TTGGCTACAATTGTCTGTTCAACCCACGAAATTCCAATGCTTATCAGAAGGAAGGAGAAA
AAGGATTATGGTACTAAACGGCTTATAGAAGGGGCTGTTAATCCAGGAGACACCTGCTTG
ATCATTGAAGATGTTGTGTCCAGCGGATCTAGTGTTTGGGAAACTGCTGAGGTTCTTCAG
AAAGAAGGCTTGAAGGTCACTGACGCTGTAGTGCTGGTGGACAGAGAGCAGGGGGGCAGG
GACAATCTGCAGGCCCGTGGGATTCGTCTCCACTCAGTGTGCACATTGTCCACAGTGCTG
TGTATTCTTGAGCAACAGAAGAAAATCAATGCTGAGACTGTGGAGAGAGTGAAGAGATTT
ATTCAGGAGAATGCTTTTGTGGCAGCTAACCCTAATGATTCTCTCCCTTCTGTGAAGAAA
GAACCCAAAGAACTAAGTTTTGGTGCACGTGCAGAGCTGCCTGGGACCCACCCGGTTGCA
GCGAAGCTTCTCAGGCTTATGCAAAAGAAGGAGACCAATCTGTGTCTGTCTGCTGATGTT
TCAGAGTCCAGAGAGCTGCTGCAGCTAGCAGATGCTTTGGGATCCAGAATCTGCTTGCTT
AAGATTCATGTAGATATTTTGAATGATTTTACTCTGGATGTGATGAAGGAGTTAACCACT
CTGGCAAAACGCCATGAGTTTCTAATTTTTGAAGACCGGAAATTTGCAGATATAGGAAAC
ACAGTAAAAAAGCAGTATGAAGGTGGGGTCTTTAAAATAGCTTCCTGGGCAGATCTTGTG
AATGCTCACGCCGTGCCCGGCTCAGGAGTTGTGAAAGGCCTGGAAGAAGTCGGCCTGCCA
CTGCACCGGGCGTGCCTCCTTGTTGCAGAAATGAGCTCTGCTGGCACCTTGGCTACTGGG
AGCTACACTGAGGCAGCAGTGCAAATGGCTGAAGAACATTCTGAATTTGTGATTGGTTTT
ATTTCTGGCTCCCGAGTAAGCATGAAACCAGAATTTCTTCACTTGACTCCAGGAGTTCAG
TTAGAAGCAGGAGGTGATAATCTCGGCCAGCAGTACCACAGCCCACAAGAAGTCATCGGC
AAACGAGGCTCTGATATCATCATTGTGGGCCGGGGCATAATAGCATCAGCTAATCAGCTG
GAAGCAGCCAAGATGTACAGAAAAGCTGCTTGGGAAGCTTACTTGAGTAGACTTGCTGTT
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 480 |
| Molecular Weight
| 52229.0 |
| Theoretical pI
| 6.36 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Uridine 5'-monophosphate synthase
MAAADALLGSLVTGLYDVQAFKFGNFVLKSGLSSPVYIDLRGIISRPSILNQVAEMLFQT
AENAEINFDTVCGVPYTALPLATIVCSTHEIPMLIRRKEKKDYGTKRLIEGAVNPGDTCL
IIEDVVSSGSSVWETAEVLQKEGLKVTDAVVLVDREQGGRDNLQARGIRLHSVCTLSTVL
CILEQQKKINAETVERVKRFIQENAFVAANPNDSLPSVKKEPKELSFGARAELPGTHPVA
AKLLRLMQKKETNLCLSADVSESRELLQLADALGSRICLLKIHVDILNDFTLDVMKELTT
LAKRHEFLIFEDRKFADIGNTVKKQYEGGVFKIASWADLVNAHAVPGSGVVKGLEEVGLP
LHRACLLVAEMSSAGTLATGSYTEAAVQMAEEHSEFVIGFISGSRVSMKPEFLHLTPGVQ
LEAGGDNLGQQYHSPQEVIGKRGSDIIIVGRGIIASANQLEAAKMYRKAAWEAYLSRLAV
|
| External Links |
|---|
| GenBank ID Protein
| CAA46253.1 |
| UniProtKB/Swiss-Prot ID
| P31754 |
| UniProtKB/Swiss-Prot Entry Name
| UMPS_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| X65125 |
| GeneCard ID
| UMPS |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
