| Identification |
|---|
| BMDB Protein ID
| BMDBP00990 |
| Secondary Accession Numbers
| |
| Name
| Aldehyde dehydrogenase, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| ALDH2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Not Available |
| Pathways
|
- Acetate from ethanol: step 2/2
- Alcohol metabolism
- Ethanol Degradation
|
| Reactions
|
| (S)-Methylmalonic acid semialdehyde + NAD + Water → Methylmalonic acid + NADH |
details
|
| 5-Hydroxyindoleacetaldehyde + NAD + Water → 5-Hydroxyindoleacetic acid + NADH |
details
|
| Pyruvaldehyde + NAD → Pyruvic acid + NADH + Water |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 17 |
| Locus
| Not Available |
| SNPs
| ALDH2 |
| Gene Sequence
|
>1563 bp
ATGTTGCGCGCCGTTGCGCTTGCCGCCGCCCGCCTCGGACCCCGCCAGGGCCGCCGCCTG
CTGTCCGCCGCCACCCAGGCCGTGCCGACCCCCAACCAGCAGCCTGAAGTCTTGTACAAC
CAGATCTTTATAAACAATGAGTGGCATGATGCCGTCAGCAAGAAAACCTTCCCCACGGTC
AATCCATCCACTGGGGATGTCATCTGTCACGTGGCTGAAGGGGACAAGGCAGACGTGGAC
AGAGCAGTGAAGGCTGCCCGGGCCGCATTCCAGCTGGGCTCGCCCTGGCGCCGCATGGAC
GCGTCCGAGAGGGGCCGGCTGCTGAACCGCCTGGCTGATCTGATTGAGCGAGACCGGACC
TACTTGGCAGCCTTGGAGACCCTGGACAACGGCAAGCCCTATATCATCTCCTACCTGGTG
GATCTGGACATGGTCCTCAAGTGCCTGCGTTACTATGCCGGCTGGGCTGACAAATACCAT
GGGAAAACCATTCCCATTGACGGGGACTACTTCAGCTACACCCGCCATGAACCTGTGGGA
GTGTGTGGGCAGATCATCCCATGGAACTTCCCGCTCCTGATGCAAGCCTGGAAACTGGGC
CCAGCCTTGGCGACGGGAAACGTGGTTGTGATGAAGGTGGCTGAGCAGACTCCACTCACT
GCCCTCTATGTGGCCAACCTGATTAAGGAGGCTGGCTTTCCTCCGGGTGTGGTCAATGTT
ATTCCTGGATTTGGCCCCACGGCGGGAGCTGCCATCGCCTCCCATGAGGACGTGGACAAA
GTGGCTTTCACCGGCTCCACTGAGGTTGGCCACCTAATCCAGGTTGCTGCGGGGAAGAGT
AACCTCAAGAGAGTGACCCTGGAGCTAGGAGGAAAGAGTCCCAATATCATCATGTCAGAT
GCTGATATGGACTGGGCCGTGGAGCAGGCCCACTTCGCCCTGTTCTTCAACCAGGGCCAG
TGCTGCTGTGCAGGCTCGCGGACCTTTGTGCAGGAGGACATTTACGCCGAGTTTGTGGAA
CGGAGTGTTGCCCGGGCCAAGTCTCGTGTGGTTGGGAACCCCTTTGACAGCCGGACTGAG
CAGGGGCCGCAGGTGGATGAAACGCAGTTTAAGAAGGTCCTTGGCTATATCAAATCTGGG
AAGGAGGAGGGGGCGAAGCTGCTGTGTGGTGGAGGGGCGGCTGCTGACCGTGGCTACTTC
ATCCAGCCCACTGTGTTTGGAGACGTGCAAGATGGCATGACCATCGCAAAGGAGGAGATC
TTTGGGCCAGTGATGCAGATTCTGAAGTTCAAGAGCATGGAGGAAGTCGTCGGGAGAGCC
AACAATTCCAAGTACGGGCTGGCTGCAGCTGTCTTCACGAAGGACTTGGACAAGGCCAAT
TACCTGTCCCAGGCCCTCCAGGCTGGCACTGTGTGGGTCAACTGCTATGACGTGTTTGGG
GCCCAGTCGCCGTTCGGTGGCTACAAGCTGTCTGGGAGTGGCCGGGAGCTGGGGGAATAC
GGGCTGCAGGCGTACACCGAAGTGAAGACCGTCACAGTCAGAGTTCCTCAGAAGAACTCC
TAA
|
| Protein Properties |
|---|
| Number of Residues
| 520 |
| Molecular Weight
| 56653.0 |
| Theoretical pI
| 7.73 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Aldehyde dehydrogenase, mitochondrial
MLRAVALAAARLGPRQGRRLLSAATQAVPTPNQQPEVLYNQIFINNEWHDAVSKKTFPTV
NPSTGDVICHVAEGDKADVDRAVKAARAAFQLGSPWRRMDASERGRLLNRLADLIERDRT
YLAALETLDNGKPYIISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDYFSYTRHEPVG
VCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNV
IPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQVAAGKSNLKRVTLELGGKSPNIIMSD
ADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYAEFVERSVARAKSRVVGNPFDSRTE
QGPQVDETQFKKVLGYIKSGKEEGAKLLCGGGAAADRGYFIQPTVFGDVQDGMTIAKEEI
FGPVMQILKFKSMEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFG
AQSPFGGYKLSGSGRELGEYGLQAYTEVKTVTVRVPQKNS
|
| External Links |
|---|
| GenBank ID Protein
| AAI16085.1 |
| UniProtKB/Swiss-Prot ID
| P20000 |
| UniProtKB/Swiss-Prot Entry Name
| ALDH2_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC116084 |
| GeneCard ID
| ALDH2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
