| Identification |
|---|
| BMDB Protein ID
| BMDBP00973 |
| Secondary Accession Numbers
| None |
| Name
| Ubiquitin-conjugating enzyme E2 H |
| Synonyms
|
Not Available
|
| Gene Name
| UBE2H |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ATP binding |
| Specific Function
| Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. E2 ubiquitin conjugating enzyme that transfers ubiquitin to MAEA, a core component of the CTLH E3 ubiquitin-protein ligase complex. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A. |
| Pathways
|
- Protein modification
- Protein ubiquitination
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 4 |
| Locus
| Not Available |
| SNPs
| UBE2H |
| Gene Sequence
|
>552 bp
ATGTCATCCCCTAGTCCGGGCAAGAGGCGGATGGACACGGACGTGGTCAAGCTTATTGAG
AGTAAGCATGAGGTTACTATCCTAGGAGGACTCAATGAATTTGTAGTGAAGTTTTATGGA
CCACAAGGAACACCGTATGAAGGCGGAGTATGGAAAGTTAGAGTGGATCTTCCTGATAAA
TACCCTTTCAAATCTCCTTCTATAGGATTCATGAATAAAATTTTCCATCCCAACATTGAT
GAAGCGTCAGGAACTGTGTGTCTAGATGTAATTAATCAAACTTGGACAGCTCTCTATGAT
CTTACCAATATATTTGAGTCCTTCCTGCCCCAGTTGTTGGCCTATCCCAACCCCATAGAT
CCTCTCAATGGTGACGCTGCAGCTATGTACCTCCATCGACCAGAAGAATACAAGCAGAAA
ATTAAAGAGTACATCCAGAAATATGCAACGGAGGAGGCACTGAAAGAGCAGGAAGAGGGC
ACTGGAGACAGCTCATCGGAGAGTTCTATGTCTGACTTTTCGGAAGACGAGGCCCAGGAT
ATGGAGTTGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 183 |
| Molecular Weight
| 20655.0 |
| Theoretical pI
| 4.29 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Ubiquitin-conjugating enzyme E2 H
MSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFVVKFYGPQGTPYEGGVWKVRVDLPDK
YPFKSPSIGFMNKIFHPNIDEASGTVCLDVINQTWTALYDLTNIFESFLPQLLAYPNPID
PLNGDAAAMYLHRPEEYKQKIKEYIQKYATEEALKEQEEGTGDSSSESSMSDFSEDEAQD
MEL
|
| External Links |
|---|
| GenBank ID Protein
| AAI09503.1 |
| UniProtKB/Swiss-Prot ID
| Q32LN1 |
| UniProtKB/Swiss-Prot Entry Name
| UBE2H_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC109502 |
| GeneCard ID
| UBE2H |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
