| Identification |
|---|
| BMDB Protein ID
| BMDBP00800 |
| Secondary Accession Numbers
| |
| Name
| D-2-hydroxyglutarate dehydrogenase, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| D2HGDH |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Catalyzes the oxidation of D-2-hydroxyglutarate to alpha-ketoglutarate. |
| Pathways
|
Not Available
|
| Reactions
|
| Eicosanoyl-CoA + Dihydroxyacetone phosphate → DHAP(18:0) + Coenzyme A |
details
|
| DHAP(18:0) + Octadecanol → DHAP(18:0e) + Stearic acid |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| Not Available |
| SNPs
| D2HGDH |
| Gene Sequence
|
>1635 bp
ATGATGATGCCCCGTCTGGTGCCCCGGTGGCCTGCGTGGCTCTTCTGCTGGCGGGCAGCC
TGCATTCAGGGAGCCTCTGTGAGACAGAAGATGTGGGCAGGGCCGTCCAAGATCCCTGGG
CTGGGCGGCCCGCGAGGGGCCTGGGGCACCAGCCCCCTGGTTCCACGAGGCAGCTGCTCA
GCCTCCTCCCGCACTCCTGAGGTGACGCTGACCCCGGAGCGGTACCCTGTGCAGCGGCTG
CCCTTCTCCGTGGTGTCTGAGGACGACCTGGCCGCCCTGGAGCGAGTCGTCCCTGGCAGG
GTCATCACAGACCCGGAGGAGCTTGAGCCTCCCAACGTGGACTGGCTGAGGACAGTCCGA
GGTTCCAGCAAGGTGCTGCTGAGGCCGCGGACGACCCAGGAGGTGGCACACATCCTCAGG
TACTGCCACGAGCGGAACCTGGCTGTGAACCCACAGGGGGGCAACACAGGCATGGTGGGC
GGCAGCACACCCGTCTTCGACGAGATCATTCTGTCCACCGCCCTAATGAACCAGGTCCTC
AGCTTTCATGACGTGTCGGGGGTCCTGGTCTGCCAGGCGGGGTGTGTCTTGGAGGCGCTG
AGCCAGTACGTGGAGGAGCGGGGCTTCATCATGCCTTTGGACCTCGGGGCGAAGGGCAGC
TGCCACATCGGGGGGAATGTGGCCACCAACGCAGGCGGCCTGCGGGTCCTGCGATACGGC
TCCCTGCGGGGGACGGTCCTGGGCCTGGAAGTGGTGCTGGCCGACGGAACCGTCCTGAAC
TGCCTCACGTCTCTTCGAAAGGACAACACGGGCTACGACCTGAAGCAGCTCTTCATTGGG
TCAGAGGGCACCCTGGGGGTCATCACGGCTGTGTCCATTCTGTGTCCGCCCAAGCCCAGC
ACTGTGAACGTGGCCTTCCTCGGCTGTCCGGGCTTTGCTGAAGTTCTGCAGACCTTCCGC
ACCTGCAGGGCAATGCTGGGCGAGATCCTGTCTGCGTTTGAGTTCATGGACGCTGAGTGC
ATGAAGCTGGTCAGGCTCCACCTCGGTCTCTCCTGCCCCGTGCAAGAAAGCCCCTTCTAC
GTCCTCATTGAGACGGCGGGCTCTGGGCCGGGGCACGATGCCGAAAAGCTGGGCTGCTTC
CTGGAGCAGGTGCTGGATTCGGGGCTGGTGACCGATGGGACCCTGGGCAGTGACGAGAGG
AGGATCAAGATGCTGTGGGCACTCAGGGAGAGGATCACTGAGGCCCTGAGCCATGACGGC
TACGTGTACAAGTACGACCTCTCGCTGCCCCTGGACCAGCTCTACGACCTCGTGGGCGAC
CTGCGTGCCCGGCTCGGCCCAAGCGCCAAGCACGTGGTGGGCTACGGCCACCTGGGGGAC
GGGAACCTGCATCTCAACGTGACGTCTGAGGCCTTCAGCACGTCCCTGCTGGGTGCCCTG
GAGCCCTACGTGTACGAGTGGACAGCGGGGCAGCGGGGTAGTGTCAGCGCCGAGCACGGC
CTGGGCTTCAAGAAGAAGGACGTCCTCGGCTACAGCAAGCCCCCTGAGGCGCTGCAGCTC
ATGAGGCAGCTCAAGGCCCTCCTGGACCCCAAGGGCATCCTGAACCCCTACAAGATGCTG
CCCACCCACGCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 544 |
| Molecular Weight
| 59056.0 |
| Theoretical pI
| 7.42 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 6-31
- 67-86
- 98-117
- 137-158
- 164-184
- 196-222
|
| Protein Sequence
|
>D-2-hydroxyglutarate dehydrogenase, mitochondrial
MMMPRLVPRWPAWLFCWRAACIQGASVRQKMWAGPSKIPGLGGPRGAWGTSPLVPRGSCS
ASSRTPEVTLTPERYPVQRLPFSVVSEDDLAALERVVPGRVITDPEELEPPNVDWLRTVR
GSSKVLLRPRTTQEVAHILRYCHERNLAVNPQGGNTGMVGGSTPVFDEIILSTALMNQVL
SFHDVSGVLVCQAGCVLEALSQYVEERGFIMPLDLGAKGSCHIGGNVATNAGGLRVLRYG
SLRGTVLGLEVVLADGTVLNCLTSLRKDNTGYDLKQLFIGSEGTLGVITAVSILCPPKPS
TVNVAFLGCPGFAEVLQTFRTCRAMLGEILSAFEFMDAECMKLVRLHLGLSCPVQESPFY
VLIETAGSGPGHDAEKLGCFLEQVLDSGLVTDGTLGSDERRIKMLWALRERITEALSRDG
YVYKYDLSLPLDRLYDLVGDLRARLGPSAKHVVGYGHLGDGNLHLNVTSEAFSTSLLGAL
EPYVYEWTAGQRGSVSAEHGLGFKKKDVLGYSKPPEALQLMRQLKALLDPKGILNPYKML
PTHA
|
| External Links |
|---|
| GenBank ID Protein
| ABF57376.1 |
| UniProtKB/Swiss-Prot ID
| Q1JPD3 |
| UniProtKB/Swiss-Prot Entry Name
| D2HDH_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT025420 |
| GeneCard ID
| D2HGDH |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
