| Identification |
|---|
| BMDB Protein ID
| BMDBP00652 |
| Secondary Accession Numbers
| None |
| Name
| Exopolyphosphatase PRUNE1 |
| Synonyms
|
Not Available
|
| Gene Name
| PRUNE1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1 (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| Not Available |
| SNPs
| PRUNE1 |
| Gene Sequence
|
>1362 bp
ATGGAGAACTACCTGCAGGGTTGTCGAGCTGCTCTGCAGGAGTCCCGACCCATACATGTT
GTGCTGGGAAATGAAGCCTGTGACTTGGACTCCATGGTGTCAGCCCTTGCCCTGGCTTTT
TACCTGGCAAAGACAACTGAGGCGGAGGAAGTCTTTGTGCCAGTGTTAAATATAAAACGT
TCAGAGCTACCTCTACGAGGTGACAATGTCTTCTTCCTTCAGAAGATTCACATTCCAGAG
TCCGTCTTGATTTTCCGGGATGAGATTGACCTCCATGCACTGCACCAGGCTGGCCAGCTC
ACCCTCATCCTTGTTGACCATCATGTCTTACCCAAAAGTGACGCAGCCCTAGAGGAGGCA
GTGGCAGAGGTGCTAGACCATCGGCCCATCGATCAGAGACACTGCCCTCCCTGCCATGTT
TCAGTTGAACTGGTGGGGTCCTGCGCTACCCTGGTGGCCGAGAGAATCCTGCAGGGGGCA
CCAGAGATCTTGGACAGGCAAACTGCAGCCCTTCTTCATGGAACAATCCTCCTGGACTGT
GTGAACATGGACCTTAAGATTGGAAAGGCAACCCTCAAGGACAGCCACTATGTAGAGAAG
CTGGAGGCCCTCTTCCCAGATCTGCCCAGCAGAAATGACATCTTTGATTCTCTGCAAAAG
GCCAAGTTTGATGTATCAGGACTGACCACAGAGCAGATGCTGAGAAAGGACCAGAAGACC
ATCTCCAGACAAGGCACTAAGGTGGCCATTAGTGCAATATATATGGATATGGAGGCTTTT
CTGCAGAGGTCTGGCCTCCTTGCAGATCTCCGTGCCTTCTGCCAGGCTCATAGCTACGAT
GCCCTGGTTGCCATGACTATCTTTTTCAACACTTACAATGAGCCAGTGCGGCAGTTGGCT
GTTTTCTGTCCCCACGCAGCACTTCGAATGACGATCTGTGGAATCCTGGAACATTCCCAC
TCTCCACCCCTGAAGCTGACCCCTGTCCCAAGCAGCCACCCTGACCTCCAAGCCTATCTT
CAAGGCAACACCCAGATCTCTCGAAAGAAAGTTCTGCCTCTGCTCCAGGAAGCCCTGTCA
GCGTATTTTGACTCCACGAACATCCCTTTAGGACAGCCTGAGACAGAGGGTGTGTCAAGG
GAACAGGTGGACAAAGAATTGGACAGGGCAGGCAACTCCCTGCTTTCTGGACTGAGTCAG
GATGAGGAGGAGCCTCCACTGCCCCCCACGCCCATGAACAGCCTGGTGGACGAGTGCCCC
CTGGATCAGGGGCTGCCGAAGTTCTCAGCCGAAGTCATCTTCGAGAAATGTAGTCAGATC
TCGCTGTCAGAACCTACCACTGCCTCCCTGTCTAAGAAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 453 |
| Molecular Weight
| 50080.0 |
| Theoretical pI
| 5.02 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Protein prune homolog
MENYLQGCRAALQESRPIHVVLGNEACDLDSMVSALALAFYLAKTTEAEEVFVPVLNIKR
SELPLRGDNVFFLQKIHIPESVLIFRDEIDLHALHQAGQLTLILVDHHVLPKSDAALEEA
VAEVLDHRPIDQRHCPPCHVSVELVGSCATLVAERILQGAPEILDRQTAALLHGTILLDC
VNMDLKIGKATLKDSHYVEKLEALFPDLPSRNDIFDSLQKAKFDVSGLTTEQMLRKDQKT
ISRQGTKVAISAIYMDMEAFLQRSGLLADLRAFCQAHSYDALVAMTIFFNTYNEPVRQLA
VFCPHAALRMTICGILEHSHSPPLKLTPVPSSHPDLQAYLQGNTQISRKKVLPLLQEALS
AYFDSTNIPLGQPETEGVSREQVDKELDRAGNSLLSGLSQDEEEPPLPPTPMNSLVDECP
LDQGLPKFSAEVIFEKCSQISLSEPTTASLSKK
|
| External Links |
|---|
| GenBank ID Protein
| AAX08800.1 |
| UniProtKB/Swiss-Prot ID
| Q5E9Y6 |
| UniProtKB/Swiss-Prot Entry Name
| PRUN1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT020783 |
| GeneCard ID
| PRUNE1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
