| Identification |
|---|
| BMDB Protein ID
| BMDBP00636 |
| Secondary Accession Numbers
| None |
| Name
| Nicotinate-nucleotide pyrophosphorylase [carboxylating] |
| Synonyms
|
Not Available
|
| Gene Name
| QPRT |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Coenzyme transport and metabolism |
| Specific Function
| Involved in the catabolism of quinolinic acid (QA). |
| Pathways
|
- Cofactor biosynthesis
- NAD(+) biosynthesis
- Nicotinate and Nicotinamide Metabolism
- Nicotinate D-ribonucleotide from quinolinate: step 1/1
|
| Reactions
|
| Nicotinic acid mononucleotide + Pyrophosphate + Carbon dioxide → Quinolinic acid + Phosphoribosyl pyrophosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 25 |
| Locus
| Not Available |
| SNPs
| QPRT |
| Gene Sequence
|
>900 bp
ATGGACCCTGAAGGCCTGGCGCATCTGCTGCCTCCTGCCACTCTGGCCGCCCTGGCAGAC
AGCTGGCTCCGAGAGGACTGCCCAGGCCTCAACTACGTGGCCTTGGTCTCGGGGACAGCC
CCCTCGCAGGCGGTGCTGTGGGCCAAGTCCCCAGGGGTGCTGGCAGGGAGGCCCTTCTTA
GATGCCATCTTTGCCCAAGTCAACTGCCAGGTCTCCTGGTTTCTCCCTGAGGGGTCAAAG
CTGGTGCCTGTGGCCAAGGTGGCCGAGGTCCGGGGCCCTGCCCACTGCCTGCTGCTGGGG
GAGCGGGTGGCCCTTAACACGCTGGCCCGCTGTAGCGGAGTTGCCAGCATGGCTGCCGCT
GCGGTAGAGACCGCCAGGGGGACCGGCTGGGCCGGACATGTGGCAGGCACGAGGAAGACT
ACACCAGGCTTCCGGCTGGTGGAGAAATACGGGCTCCTAGTGGGCGGGGCTGCCGCCCAC
CGCTACGACCTTGGCGGGCTGGTGATGGTGAAGGACAACCATGTCATGGCAGCCGGTGGT
GTGAAAAAGGCGGTGCGGGCGGCGCGGCGGGCGGCCGACTTCGCCCTGAAGGTGGAGGTG
GAGTGCAGCAGCCTGCAGGAGGCTGTGGAGGCGGCCGAGGCAGGAGCGGACCTCGTCTTG
CTGGACAACTTCAGGCCTGAGGAGCTGCACCCCACGGCCGCCACGCTGAAGGCCCAGTTC
CCCAGTGTGAGTGTGGAGGCCAGCGGGGGCGTCAGGCTGGACAACCTCCCGCAGTTCTGT
GGGCCCCACATCGATGTCATCTCTTTGGGGATGCTGACGCAGGCGGCCCCGGCCCTCGAT
TTCTCCCTCAAGCTGTTTGCTGAAGGGGCCACTCCAGTGCCCCACGCCCGCCGGTCCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 299 |
| Molecular Weight
| 31151.0 |
| Theoretical pI
| 7.21 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Nicotinate-nucleotide pyrophosphorylase [carboxylating]
MDPEGLAHLLPPATLAALADSWLREDCPGLNYVALVSGTAPSQAVLWAKSPGVLAGRPFL
DAIFAQVNCQVSWFLPEGSKLVPVAKVAEVRGPAHCLLLGERVALNTLARCSGVASMAAA
AVETARGTGWAGHVAGTRKTTPGFRLVEKYGLLVGGAAAHRYDLGGLVMVKDNHVMAAGG
VKKAVRAARRAADFALKVEVECSSLQEAVEAAEAGADLVLLDNFRPEELHPTAATLKAQF
PSVSVEASGGVRLDNLPQFCGPHIDVISLGMLTQAAPALDFSLKLFAEGATPVPHARRS
|
| External Links |
|---|
| GenBank ID Protein
| AAI02551.1 |
| UniProtKB/Swiss-Prot ID
| Q3T063 |
| UniProtKB/Swiss-Prot Entry Name
| NADC_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC102550 |
| GeneCard ID
| QPRT |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
