| Identification |
|---|
| BMDB Protein ID
| BMDBP00564 |
| Secondary Accession Numbers
| None |
| Name
| Aspartate--tRNA ligase, cytoplasmic |
| Synonyms
|
Not Available
|
| Gene Name
| DARS1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Translation, ribosomal structure and biogenesis |
| Specific Function
| Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. |
| Pathways
|
- Aspartate Metabolism
- Protein Synthesis: Aspartic Acid
|
| Reactions
|
| Adenosine triphosphate + L-Aspartic acid + tRNA(Asp) → Adenosine monophosphate + Pyrophosphate + L-Aspartyl-tRNA(Asp) |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| Not Available |
| SNPs
| DARS1 |
| Gene Sequence
|
>1506 bp
ATGCCCAGCGCCAACGCCAGCCGCAGGAGTCAGGAGAAGCCGCGGGAGATCATGGACGCG
GCGGAAGATTATGCAAAAGAAAGATACGGAGTATCTTCAATGATACAATCACAAGAAAAA
CCAGATCGAGTTTTGGTTCGAATTAGTGATTTGACAGTGCAAAAAGCTGGTGAAGTTGTT
TGGGTGCGTGCAAGGGTTCATACAAGCAGAGCTAAAGGAAAGCAGTGTTTCTTAGTCCTA
CGACAGCAGCAGTTTAATGTCCAGGCTCTTGTGGCGGTAGGAGACCATGCAAGCAAGCAG
ATGGTTAAATTTGCTGCCAACATCAACAAAGAGAGCATCGTTGATGTGGAAGGTGTTGTG
AGAAAAGTGAATCAGAAAATTGGAAGCTGTACACAACAAGATGTAGAGTTACATGTTCAA
AAGATTTATGTGATCAGTTCAGCTGAACCCCGCCTGCCCCTGCAGCTGGACGATGCTGTT
CGGCCTGAAGTGGAAGGAGAAGAGGAAGGAAGAGCTACTGTTAACCAGGATACGAGATTA
GACAACAGAGTCATTGATCTTAGGACATCAACTAGTCAGGCAATCTTCCGTCTCCAGTCT
GGCATCTGCCATCCTTTCCGAGAAACTTTAACTAACAAGGGTTTTGTGGAGATCCAAACT
CCTAAAATTATCTCAGCTGCCAGTGAAGGAGGAGCCAATGTATTTACTGTGTCATATTTT
AAAAATAATGCATACCTGGCTCAGTCTCCACAGCTGTACAAGCAAATGTGTATTTGTGCT
GATTTTGAGAAGGTTTTCTGTATTGGGCCAGTATTCAGAGCTGAAGACTCTAATACACAC
AGACATCTGACTGAATTTGTTGGCTTGGATATTGAAATGGCTTTTAATTACCATTACCAT
GAAGTTGTGGAAGAAATTGCCGACACTTTAGTGCAAATATTCAAAGGACTTCAGAAAAGG
TTTCAAACTGAAATTCAGACGGTGAATAAACAGTTCCCATGTGAGCCATTCAAATTTTTG
GAGCCAACTTTAAGACTAGAATACTGTGAAGCATTGGCTATGCTTAGGGAAGCTGGAATT
GAAATGGGAGATGAAGAAGATCTAAGTACACCAAATGAAAAACTGTTGGGTCGTTTGGTA
AAGGAAAAGTATGATACCGATTTTTATATTCTTGATAAATATCCATTGGCTGTAAGACCT
TTCTATACCATGCCTGACCCACGAAATCCTAAACAATCTAACTCTTATGATATGTTCATG
AGGGGAGAAGAAATACTGTCAGGAGCTCAAAGAATACATGACCCTCAGCTGGTAACAGAG
AGAGCCTTACATCATGGAATTGATTTGGAGAAAATTAAGGCATACATTGATTCCTTCCGT
TTTGGAGCCCCTCCTCATGCTGGTGGAGGCATTGGGTTGGAACGAGTGACTATGCTGTTT
TTGGGCTTGCACAATGTTCGTCAAACCTCAATGTTTCCCCGTGATCCCAAAAGACTTACT
CCTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 501 |
| Molecular Weight
| 57036.0 |
| Theoretical pI
| 6.84 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Aspartyl-tRNA synthetase, cytoplasmic
MPSANASRRSQEKPREIMDAAEDYAKERYGVSSMIQSQEKPDRVLVRISDLTVQKAGEVV
WVRARVHTSRAKGKQCFLVLRQQQFNVQALVAVGDHASKQMVKFAANINKESIVDVEGVV
RKVNQKIGSCTQQDVELHVQKIYVISSAEPRLPLQLDDAVRPEVEGEEEGRATVNQDTRL
DNRVIDLRTSTSQAIFRLQSGICHPFRETLTNKGFVEIQTPKIISAASEGGANVFTVSYF
KNNAYLAQSPQLYKQMCICADFEKVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYH
EVVEEIADTLVQIFKGLQKRFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGI
EMGDEEDLSTPNEKLLGRLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSNSYDMFM
RGEEILSGAQRIHDPQLVTERALHHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLF
LGLHNVRQTSMFPRDPKRLTP
|
| External Links |
|---|
| GenBank ID Protein
| AAI03320.1 |
| UniProtKB/Swiss-Prot ID
| Q3SYZ4 |
| UniProtKB/Swiss-Prot Entry Name
| SYDC_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC103319 |
| GeneCard ID
| DARS1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
