| Identification |
|---|
| BMDB Protein ID
| BMDBP00071 |
| Secondary Accession Numbers
| None |
| Name
| 3-ketodihydrosphingosine reductase |
| Synonyms
|
Not Available
|
| Gene Name
| KDSR |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). |
| Pathways
|
- Lipid metabolism
- Sphingolipid Metabolism
|
| Reactions
|
| Sphinganine + NADPH → 3-Dehydrosphinganine + NADP |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 24 |
| Locus
| Not Available |
| SNPs
| KDSR |
| Gene Sequence
|
>996 bp
ATGCTGCTGCTGGCCGCCGCGTCTCTCGTGGCCTTCGTGCTGCTGCTCTACATGGTGTCC
CCGCTCATCAGCCCCAAGCCCCTCGCCCTGCCCGGGGCGCACGTAGTGGTTACAGGAGGC
TCCAGTGGCATCGGAAAGTGCATTGCTATTGAGTGCTATAAACAAGGAGCCTTTATAACT
CTGGTTGCACGGAATGAGGACAAGCTGTTGCAGGCAAAGAAAGAAATCGAAAAACACTCT
ATTAATGATAAACAGGTGGTGCTTTGTATATCAGTTGATGTATCTCAAGACTATAGCCAA
GTAGAGAACGTCATAAAACAAGCGCAGGAGAAGCTGGGCCCGGTGGACATGCTTGTAAAC
TGTGCAGGAATGTCACTTTCAGGGAAATTTGAAGATCTTGAAGTTAGTACTTTTGAAAGG
CTGATGAGCATCAACTACCTGGGCAGCGTGTACCCCAGCCGGGCGGTGATCGCCACCATG
AAGGAACGCCGCATGGGCAGGGTCGTCTTCGTGTCTTCCCAGGCCGGGCAGCTGGGCCTG
TTTGGTTACACAGCATACTCTTCATCCAAGTTCGCCCTCAGGGGACTTGCGGAGGCTTTG
CAGATGGAGGTGAAGCCTTACAATGTGTATGTCACAGTTGCCTACCCACCAGACACAGAC
ACCCCTGGGTTTGCAAAAGAAAACCAAACCAAGCCTTTAGAGACACGTCTTATTTCAGAG
ACCACATCTGTCTGCAAACCAGAACAAGTGGCCAAACAAATTGTTAAAGACGTACAAGGA
AATTTCAACAGTTCCATCGGTTCCGACGGGTACATGCTCTCATCGCTGACCTGTGGAATG
GCTCCAGTAACGTCCATCATGGAAGGGCTCCAGCAGGTGGTCACCATGGGCCTCTTCCGC
ACGATCGCACTGTTTTACCTTGGAAGTTTCGACAGTATCGTTCGTCGCTGCATGATGCAG
AAGGCGAAATTGGAAACTGTAGACAAAACTGCCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 331 |
| Molecular Weight
| 36020.0 |
| Theoretical pI
| 8.24 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>3-ketodihydrosphingosine reductase
MLLLAAASLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFIT
LVARNEDKLLQAKKEIEKHSINDKQVVLCISVDVSQDYSQVENVIKQAQEKLGPVDMLVN
CAGMSLSGKFEDLEVSTFERLMSINYLGSVYPSRAVIATMKERRMGRVVFVSSQAGQLGL
FGYTAYSSSKFALRGLAEALQMEVKPYNVYVTVAYPPDTDTPGFAKENQTKPLETRLISE
TTSVCKPEQVAKQIVKDVQGNFNSSIGSDGYMLSSLTCGMAPVTSIMEGLQQVVTMGLFR
TIALFYLGSFDSIVRRCMMQKAKLETVDKTA
|
| External Links |
|---|
| GenBank ID Protein
| AAI12616.1 |
| UniProtKB/Swiss-Prot ID
| Q2KIJ5 |
| UniProtKB/Swiss-Prot Entry Name
| KDSR_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC112615 |
| GeneCard ID
| KDSR |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
