Showing metabocard for gamma-Glutamylhydroxyproline (BMDB0064155)

IdentificationTaxonomyPhysical propertiesPathwaysSpectraConcentrationsLinksReferencesXML
Record Information
Version1.0
Creation Date2020-03-03 19:44:03 UTC
Update Date2020-03-13 17:51:11 UTC
BMDB IDBMDB0064155
Secondary Accession Numbers
  • BMDB64155
Metabolite Identification
Common Namegamma-Glutamylhydroxyproline
Descriptiongamma-Glutamylhydroxyproline, also known as γ-glu-hyp or L-gamma-glu-L-hyp, belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Based on a literature review very few articles have been published on gamma-Glutamylhydroxyproline.
Structure
Thumb
MOLSDF3D-SDFPDBSMILESInChI View 3D Structure
Synonyms
ValueSource
g-GlutamylhydroxyprolineGenerator
Γ-glutamylhydroxyprolineGenerator
Γ-glu-hypHMDB
L-Γ-glu-L-hypHMDB
L-Γ-glutamyl-L-hydroxyprolineHMDB
Γ-glutamyl-hydroxyprolineHMDB
Glutamate hydroxyproline dipeptideHMDB
Glutamate-hydroxyproline dipeptideHMDB
Glutamic acid hydroxyproline dipeptideHMDB
Glutamic acid-hydroxyproline dipeptideHMDB
(4R)-L-Γ-glutamyl-4-hydroxy-L-prolineHMDB
(4R)-L-gamma-Glutamyl-4-hydroxy-L-prolineHMDB
L-gamma-Glu-L-hypHMDB
L-gamma-Glutamyl-L-hydroxyprolineHMDB
gamma-Glu-hypHMDB
gamma-Glutamyl-hydroxyprolineHMDB
(2S,4R)-1-[(4S)-4-Amino-4-carboxybutanoyl]-4-hydroxypyrrolidine-2-carboxylateHMDB
gamma-GlutamylhydroxyprolineHMDB
Chemical FormulaC10H16N2O6
Average Molecular Weight260.246
Monoisotopic Molecular Weight260.100836243
IUPAC Name(2S,4R)-1-[(4S)-4-amino-4-carboxybutanoyl]-4-hydroxypyrrolidine-2-carboxylic acid
Traditional Name(2S,4R)-1-[(4S)-4-amino-4-carboxybutanoyl]-4-hydroxypyrrolidine-2-carboxylic acid
CAS Registry NumberNot Available
SMILES
N[C@@H](CCC(=O)N1C[C@H](O)C[C@H]1C(O)=O)C(O)=O
InChI Identifier
InChI=1S/C10H16N2O6/c11-6(9(15)16)1-2-8(14)12-4-5(13)3-7(12)10(17)18/h5-7,13H,1-4,11H2,(H,15,16)(H,17,18)/t5-,6+,7+/m1/s1
InChI KeyVKENMLSUUVOQLD-VQVTYTSYSA-N
Chemical Taxonomy
Description belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
Sub ClassAmino acids, peptides, and analogues
Direct ParentDipeptides
Alternative Parents
Substituents
  • Alpha-dipeptide
  • Gamma-glutamyl alpha-amino acid
  • Glutamine or derivatives
  • Proline or derivatives
  • N-acyl-l-alpha-amino acid
  • N-acyl-alpha amino acid or derivatives
  • N-acyl-alpha-amino acid
  • L-alpha-amino acid
  • Alpha-amino acid or derivatives
  • Alpha-amino acid
  • Pyrrolidine carboxylic acid or derivatives
  • Pyrrolidine carboxylic acid
  • N-acylpyrrolidine
  • Hydroxy fatty acid
  • Heterocyclic fatty acid
  • Fatty acyl
  • Fatty acid
  • Dicarboxylic acid or derivatives
  • Tertiary carboxylic acid amide
  • Pyrrolidine
  • Amino acid
  • Secondary alcohol
  • Carboxamide group
  • Amino acid or derivatives
  • Azacycle
  • Organoheterocyclic compound
  • Carboxylic acid
  • Organic nitrogen compound
  • Organic oxygen compound
  • Organopnictogen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Primary amine
  • Organooxygen compound
  • Organonitrogen compound
  • Primary aliphatic amine
  • Carbonyl group
  • Amine
  • Alcohol
  • Aliphatic heteromonocyclic compound
Molecular FrameworkAliphatic heteromonocyclic compounds
External DescriptorsNot Available
Ontology
StatusExpected but not Quantified
OriginNot Available
BiofunctionNot Available
ApplicationNot Available
Cellular locationsNot Available
Physical Properties
StateNot Available
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP-3.5ALOGPS
logP-4.7ChemAxon
logS-0.95ALOGPS
pKa (Strongest Acidic)1.84ChemAxon
pKa (Strongest Basic)9.31ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count7ChemAxon
Hydrogen Donor Count4ChemAxon
Polar Surface Area141.16 ŲChemAxon
Rotatable Bond Count5ChemAxon
Refractivity57.59 m³·mol⁻¹ChemAxon
Polarizability24.6 ųChemAxon
Number of Rings1ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Spectra
Biological Properties
Cellular LocationsNot Available
Biospecimen LocationsNot Available
Pathways
Normal Concentrations
Not Available
Abnormal Concentrations
Not Available
HMDB IDHMDB0029150
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB112146
KNApSAcK IDNot Available
Chemspider IDNot Available
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkNot Available
METLIN IDNot Available
PubChem Compound118243642
PDB IDNot Available
ChEBI ID193275
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General ReferencesNot Available