Showing metabocard for Malonic acid (BMDB0000691)

General function:

Secondary metabolites biosynthesis, transport and catabolism

Specific function:

Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.

Gene Name:

FASN

Uniprot ID:

Q71SP7

Molecular weight:

274554.0

Reactions

General function:

Involved in neutral amino acid transmembrane transporte

Specific function:

Not Available

Gene Name:

SLC1A4

Uniprot ID:

A5HSH2

Molecular weight:

2767.0

General function:

Involved in neutral amino acid transmembrane transporte

Specific function:

Not Available

Gene Name:

SLC1A5

Uniprot ID:

A5HSH3

Molecular weight:

3937.0

General function:

Energy production and conversion

Specific function:

Not Available

Gene Name:

SLC1A6

Uniprot ID:

A6H774

Molecular weight:

61424.0

General function:

Involved in glutamate:sodium symporter activity

Specific function:

Not Available

Gene Name:

SLC1A2

Uniprot ID:

A5HSH1

Molecular weight:

2798.0

General function:

Energy production and conversion

Specific function:

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine (By similarity). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (By similarity). Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity). Contributes to glutathione biosynthesis and protection against oxidative stress via its role in L-glutamate and L-cysteine transport. Negatively regulated by ARL6IP5 (By similarity).

Gene Name:

SLC1A1

Uniprot ID:

Q95135

Molecular weight:

57297.0

General function:

Energy production and conversion

Specific function:

Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence.

Gene Name:

SLC1A4

Uniprot ID:

A2VDL4

Molecular weight:

56007.0

General function:

Energy production and conversion

Specific function:

Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids.

Gene Name:

SLC1A5

Uniprot ID:

Q95JC7

Molecular weight:

56448.0

General function:

Energy production and conversion

Specific function:

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7723632). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (By similarity). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).

Gene Name:

SLC1A3

Uniprot ID:

P46411

Molecular weight:

59591.0

General function:

Involved in glutamate:sodium symporter activity

Specific function:

Not Available

Gene Name:

SLC1A1

Uniprot ID:

A5HSH0

Molecular weight:

2632.0

General function:

Inorganic ion transport and metabolism

Specific function:

Not Available

Gene Name:

SLC13A2

Uniprot ID:

Q3SYV8

Molecular weight:

64980.0

General function:

Energy production and conversion

Specific function:

Not Available

Gene Name:

SLC1A1

Uniprot ID:

A7MB31

Molecular weight:

57126.0

General function:

Inorganic ion transport and metabolism

Specific function:

Not Available

Gene Name:

SLC13A3

Uniprot ID:

A1A4I3

Molecular weight:

66657.0

General function:

Energy production and conversion

Specific function:

Not Available

Gene Name:

SLC1A4

Uniprot ID:

Q866Q9

Molecular weight:

19247.0